Bioinformatics Interview Questions - An interviewhelper.org blog

CADD stands for ___________________________________

2009-02-28T04:33:00.000-08:00

Question :CADD stands for ___________________________________
Answer :Computer Aided drug design

The generation of messenger RNA expression profiles is referred as

2009-02-28T04:32:00.000-08:00

Question :The generation of messenger RNA expression profiles is referred as
a.transcription b. trasncriptomics c.Genomics d.RNAsyn
Answer :b

tRNA genes are identified by using

2009-02-28T04:31:00.000-08:00

Question :tRNA genes are identified by using
a. tRNAscan b.Translate tool c.Chime d. Hex
Answer :a

ARED _____________________________

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Question :ARED _____________________________
Answer :Adenylate Uridylate (AU)-Rich Element Database

--------------------- is a database that provides comprehensive information on mammalian microRNAs.

2009-02-28T04:28:00.000-08:00

Question :--------------------- is a database that provides comprehensive information on mammalian microRNAs.
a. Argonaute b.RDP c.tRNADB d. None
Answer :a

Darwin stands for -----------------------------------------------

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Question :Darwin stands for -----------------------------------------------
Answer :Data Analysis and Retrieval With Indexed Nucleotide/peptide sequences.

RDP Stands for -------------------------------------------

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Question :RDP Stands for -------------------------------------------
Answer :Ribosomal Database project

Name the software for Natural Language Processing

2009-02-28T04:25:00.000-08:00

Question :Name the software for Natural Language Processing
a. openNLP b. SPSS c. SAS d. None
Answer :a

SNNS stands for __________________________________________.

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Question :SNNS stands for __________________________________________.?
Answer :Stuttgart Neural Network Simulator

Name the software for neural network

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Question :Name the software for neural network.
a. SNNS b. Emergent c. JavaNNS d. all of the above
Answer :d

------- - is an interconnected group of artificial neurons and processes information using a connectionist approach to computation

2009-02-28T04:17:00.000-08:00

Question :------- - is an interconnected group of artificial neurons and processes information using a connectionist approach to computation.
a. Neural network b. Network c. Internetwork d. Intranetwork
Answer :d

Robotics based upon the following field

2009-02-28T03:53:00.000-08:00

Question :Robotics based upon the following field
a. Cobalt b. Mysql c.AI d. all of the above
Answer :c

----------- is the program used for natural selection and artificial phenotype selection.

2009-02-28T03:38:00.000-08:00

Question :----------- is the program used for natural selection and artificial phenotype selection. a. Genetic algorithm b. MOD c. ClustalW d. None
Answer :a

Speech recognition softwares works based on

2009-02-28T03:37:00.000-08:00

Question :Speech recognition softwares works based on
a. Cobalt b. AI c.Language d.None
Answer :b

Name the protein sequence database

2009-02-28T03:36:00.000-08:00

Question :Name the protein sequence database
a. Uniprot b.PIR c.Swiss-prot d.all of the above
Answer :d

What is the database used in ensembl

2009-02-28T03:35:00.000-08:00

Question :What is the database used in ensembl
a.Oracle b.MS-Access c.Mysql d.all of the above
Answer :c

Data mining tool used to analyse ensemble

2009-02-28T03:34:00.000-08:00

Question :Data mining tool used to analyse ensemble
a. Chime b.Rasmol c.BioMart d. None
Answer :c

How many species support provided by Ensembl as by 47th release on 2007

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Question :How many species support provided by Ensembl as by 47th release on 2007
a. 55 b.45 c.35 d.25
Answer :c

Ensembl is maintained by

2009-02-28T03:31:00.000-08:00

Question :Ensembl is maintained by
a.NCBI b. EBI c. RCSB d.NLM
Answer :b

Large genome annotated database is

2009-02-28T03:30:00.000-08:00

Question :Large genome annotated database is
a. Genbank b. Uniprot c.Ensembl d. MMDB
Answer :c

What is the percentage of Human Genome sequenced properly

2009-02-28T03:29:00.000-08:00

Question :What is the percentage of Human Genome sequenced properly?
a. 50% b.60% c.94% d.84%
Answer :c

How many groups involved in HGP

2009-02-28T03:28:00.000-08:00

Question :How many groups involved in HGP?
a.10 b.20 c.30 d.40
Answer :b

How many Protein coding genes might be present in Human Genome

2009-02-28T03:27:00.000-08:00

Question :How many Protein coding genes might be present in Human Genome?
a. 10,000 b.40,000 c. 80,000 d. None
Answer :b

What is the type of Recombination vector generally recommended for HGP

2009-02-28T03:26:00.002-08:00

Question :What is the type of Recombination vector generally recommended for HGP?
a. Plasmid b. Cosmid c. BAC d.YAC
Answer :c

When Human genome sequencing initiated

2009-02-28T03:26:00.001-08:00

Question :When Human genome sequencing initiated?
a. 1996 b.1997 c.1998 d. 1999
Answer :d

When first completed report of Human Genome was released

2009-02-28T03:25:00.001-08:00

Question :When first completed report of Human Genome was released?
a. 2000 b.2001 c. 2002 d. 2003
Answer :a

How many SNPs present in Human Genome reported by HGP

2009-02-28T03:24:00.000-08:00

Question :How many SNPs present in Human Genome reported by HGP?
a. 2.2 million b.2.1 million c. 3.3 billion d.4.2 billion
Answer :b

Which sequencing method efficiently helpful for Human Genome Project

2009-02-28T03:23:00.000-08:00

Question :Which sequencing method efficiently helpful for Human Genome Project?
a. Sanger Method b. Maxm-Gilbert method c. Whole Genome Shotgun d. None
Answer :c

When Human Genome Project work was officially started

2009-02-28T03:22:00.001-08:00

Question :When Human Genome Project work was officially started?
a. 1970 b. 1980 c. 1990 d. 2000
Answer :c

When Human Genome Project formally proposed

2009-02-28T03:21:00.000-08:00

Question :When Human Genome Project formally proposed?
a. 1975 b.1985 c.1995 d. 2005
Answer :b

Artificial Intelligence term is coined by

2009-02-28T03:20:00.000-08:00

Question :Artificial Intelligence term is coined by
a. John McCarthy b. Watson c. Meselson d. George Mitchel
Answer :a

A traditional chemist can synthesize _____________ compounds per year

2009-02-28T03:19:00.000-08:00

Question :A traditional chemist can synthesize _____________ compounds per year
a. 100-200 b. 200-300 c. 300-400 d.400-500
Answer :a

In how many centres clinical trials should be carried out

2009-02-28T03:18:00.000-08:00

Question :In how many centres clinical trials should be carried out
a. 1-2 b. 2-3 c. 3-4 d. 4-5
Answer :c

Clinical trials for Vaccine contains _________ number of phases

2009-02-28T03:16:00.000-08:00

Question :Clinical trials for Vaccine contains _________ number of phases
a. 1 b. 2 c. 3 d. 4
Answer :c

Designing a drug molecule atom by atom against a receptor or target known as

2009-02-28T03:12:00.000-08:00

Question :Designing a drug molecule atom by atom against a receptor or target known
a. Denovo b. QSAR c. Pharmacophore mapping d. Docking
Answer :a

Hex software used for

2009-02-28T03:11:00.000-08:00

Question :Hex software used for
a. alignment b. Viewer c. Docking d. None
Answer :c

How many patients should be studied for clinical Phase II trial

2009-02-28T03:10:00.000-08:00

Question :How many patients should be studied for clinical Phase II trial
a.10-15 b. 20-25 c. 30-35 d. 40-45
Answer :b

________________ is 3D protein viewer

2009-02-28T03:09:00.000-08:00

Question :________________ is 3D protein viewer
a. Marvin space b. Rasmol c. Swiss PDB Viewer d. All
Answer :d

_________ should approve proposed clinical trial for drug designing

2009-02-28T03:08:00.000-08:00

Question :_________ should approve proposed clinical trial for drug designing
a. DCGI b. DIG c. President d. Prime Minister
Answer :a

How many phases of clinical trials should be carried out

2009-02-28T03:07:00.000-08:00

Question :How many phases of clinical trials should be carried out
a. 1 b. 2 c. 3 d. 4
Answer :d

Quarternary structure predicted by

2009-02-28T03:06:00.000-08:00

Question :Quarternary structure predicted by
a. SWISS-MODEL b. Mercury c. Mericity d. Quantum
Answer :c

Abinitio approach of tertiary prediction achieved by

2009-02-28T03:05:00.002-08:00

Question :Abinitio approach of tertiary prediction achieved by
a. SWISS-MODEL b. 3DPSSM c. Phyre d. Rosetta
Answer :d

3DPSSM predicts tertiary structure through

2009-02-28T03:05:00.001-08:00

Question :3DPSSM predicts tertiary structure through
a. Homology b. Threading c. Abinitio d. All
Answer :b

Homology Modelling server is

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Question :Homology Modelling server is
a. SWISS-MODEL b. 3DPSSM c. Phyre d. Rosetta
Answer :a

Secondary structure predicted by

2009-02-28T02:43:00.001-08:00

Question :Secondary structure predicted by
a. GOR b. COILS c. Nnpred d. All
Answer :d

Following tool used for primary structure analysis

2009-02-28T02:40:00.000-08:00

Question :Following tool used for primary structure analysis
a. SAPS b. PAPS c. PrimAna d. PriPred
Answer :a

Phylogenetic analysis tools include

2009-02-28T02:39:00.000-08:00

Question :Phylogenetic analysis tools include
a. Phylip b. PAUP c. Both d. None
Answer :c

Which alignment might be useful for phylogenetic analysis

2009-02-28T02:38:00.000-08:00

Question :Which alignment might be useful for phylogenetic analysis
a. Pair-wise b. Multiple c. Both d. None
Answer :b

Tool used for Local alignment is

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Question :Tool used for Local alignment
a. BLAST b. ClustalW c. ORF Finder d. Genscan
Answer :a

Pair-wise alignment include

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Question :Pair-wise alignment include
a. Local b. Global c. Both d. None
Answer :c

Which type of BLOSUM matrix mostly used

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Question :Which type of BLOSUM matrix mostly used
a. BLOSUM62 b. BLOSUM72 c. BLOSUM82 d. BLOSUM92
Answer :a

Which type of PAM matrix mostly used

2009-02-28T02:34:00.000-08:00

Question :Which type of PAM matrix mostly used
a. PAM 100 b. PAM150 c. PAM200 d. PAM250
Answer :d

Characters are homologous with conserved function known as

2009-02-28T02:33:00.000-08:00

Question :Characters are homologous with conserved function known as
a. Analogous b. Orthologous c. Paralogous d. Xenologous
Answer :b

Translate tool at ExPASy provides, how many number of frames of frames of translation

2009-02-28T02:32:00.000-08:00

Question :Translate tool at ExPASy provides, how many number of frames of frames of translation
a. 3 b.4 c.5 d. 6
Answer :d

Gene prediction tool at NCBI is

2009-02-28T02:31:00.000-08:00

Question :Gene prediction tool at NCBI is
a. Genscan b. Genefinder c. ORF finder d. All
Answer :c

Before analyzing sequence, it can be converted into different formats using

2009-02-28T02:29:00.000-08:00

Question :Before analyzing sequence, it can be converted into different formats using ?
a. Formcon b. Readseq c. Readcon d. Confor
Answer :b

Server which predicts the presence and location of signal peptide cleavage sites is

2009-02-28T00:23:00.000-08:00

Question :Server which predicts the presence and location of signal peptide cleavage sites is ?
a. Sigpred b. SignalI c. SignalP d.Sigprepred.
Answer :b

BLAST is ___________________________________________

2009-02-28T00:21:00.000-08:00

Question :BLAST is ___________________________________________?
Answer :Basic Local Alignment Search Tool

VAST is ____________________________________________

2009-02-28T00:20:00.000-08:00

Question :VAST is ____________________________________________ ?
Answer :Vector Alignment Search Tool

It is a freely accessible database of protein and genetic interactions

2009-02-28T00:19:00.000-08:00

Question :It is a freely accessible database of protein and genetic interactions
a. GOD b.Motif c. BIOGRID d. None
Answer :c

ADME-TOX Prediction tool is

2009-02-28T00:18:00.000-08:00

Question :ADME-TOX Prediction tool is
a. ADME predictor b. ADME pr c. ADME cal d. None
Answer :a

Leads means

2009-02-28T00:17:00.000-08:00

Question :Leads means
a. Chemical b. drug c. Possible drug d. All
Answer :c

How many ways Denovo designing might be used for drug designing

2009-02-28T00:16:00.000-08:00

Question :How many ways Denovo designing might be used for drug designing .
a. 1 b. 2 c. 3 d. 4
Answer :b

_________________ is an example for automated docking program

2009-02-28T00:14:00.000-08:00

Question :_________________ is an example for automated docking program
a. Hex b. Argus Lab c. Autodock d. VegaZZ
Answer :c

. Lipinski’s rule states that the drug has not more than ________ hydrogen bond donors

2009-02-27T23:12:00.000-08:00

Question :. Lipinski’s rule states that the drug has not more than ________ hydrogen bond donors?
a. 2 b. 3 c. 4 d. 5
Answer :d

Pharmacophore term defined by

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Question :Pharmacophore term defined by
a. Pauling b. Ehrlich c. Koshland d. Watson
Answer :b

Pharmacophore term defined by

2009-02-27T23:11:00.000-08:00

Question :Pharmacophore term defined by
a. Pauling b. Ehrlich c. Koshland d. Watson
Answer :b

The study of the effects of drugs on tissues and organs is called as

2009-02-27T23:10:00.000-08:00

Question :The study of the effects of drugs on tissues and organs is called as
a. Pharmacodynamcis b. Pharmacokinetics c. Pharmacophore d. All
Answer :a

BioEdit used for

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Question :BioEdit used for
a. Similarity studies b. Structure Prediction c. Profile search d. Motif search
Answer :a

HMM stands for _____________________________

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Question :HMM stands for _____________________________ ?
Answer :Hidden Markov Model

ORF stands for ______________________________

2009-02-27T23:07:00.000-08:00

Question :ORF stands for ______________________________ ?
Answer :Open Reading Frame

PSSM stands for _____________________________

2009-02-27T23:06:00.000-08:00

Question :PSSM stands for _____________________________
Answer :Position Specific Scoring Matrix

Phylip stands for _____________________________

2009-02-27T23:05:00.000-08:00

Question :Phylip stands for _____________________________
Answer :Phylogeny Inference Package

Which components of Marvin Beans used for structure drawing

2009-02-27T23:03:00.000-08:00

Question :Which components of Marvin Beans used for structure drawing
a. Marvin Sketch b. Marvin View c. Marvin space d. All
Answer :a

Pathway prediction system of UM-BBD predicts pathway from

2009-02-27T23:02:00.000-08:00

Question :Pathway prediction system of UM-BBD predicts pathway from
a. SMILES b. structures c. Both d. None
Answer :c

Which pathway database based on reference pathway maps

2009-02-27T23:01:00.000-08:00

Question :Which pathway database based on reference pathway maps:
a. Metacyc b. Ecocyc c. KEGG pathway d. UM-BBD
Answer :c

Which produces the abinitio prediction of protein function from sequence

2009-02-27T23:00:00.000-08:00

Question :Which produces the abinitio prediction of protein function from sequence?
a. ProtFun b. PFP Server c. Pratt d. All
Answer :a

____________ tool used for Pattern construction

2009-02-27T22:55:00.000-08:00

Question :____________ tool used for Pattern construction
a. Pratt b. Patcons c. Both d. None
Answer :a

__________ finds structural and sequence motifs in protein sequence

2009-02-27T22:52:00.000-08:00

Question :__________ finds structural and sequence motifs in protein sequence
a. Patsearch b. Prosear c. ProfileScan d. Prof
Answer :c

Mathemtical representation of Conserved region known as

2009-02-27T22:50:00.000-08:00

Question :Mathemtical representation of Conserved region known as
a. Motif b. Profile c. Pattern d. Module
Answer :b

Vadar used for

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Question :. Vadar used for
a. Alignment b. Structure prediction c. Structure validation d. None
Answer :c

Books available in the following site

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Question :Books available in the following site
a. EMBL b. NCBI c. RCSB d. PIR
Answer :b

KEGG is an structural database

2009-02-27T22:46:00.000-08:00

Question :KEGG is an structural database
a. true b. false
Answer :b

1Hae is an ID of the following databse

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Question :1Hae is an ID of the following databse
a. EMBL b. Genbank c. PDB d. Uniprot
Answer :c

First biological database was made by

2009-02-27T22:40:00.000-08:00

Question :First biological database was made by
a. Dayhoff b. Darwin c. Pauling d. Markov
Answer :a

ClustalW used for

2009-02-27T22:31:00.000-08:00

Question :ClustalW used for
a. Structure prediction b. Motif analysis c. Multiple sequence alignment d. None
Answer :c

In CATH, T – represents

2009-02-27T22:16:00.000-08:00

Question :In CATH, T – represents:
a. Torsion b. Topology c. Target d. tRNA
Answer :b

An automated comparative protein modeling server is

2009-02-27T22:15:00.000-08:00

Question :An automated comparative protein modeling server is:
a. BLAST b. VAST c. SWISS-MODEL d. DALI
Answer :c

. PDB managed by

2009-02-27T22:14:00.000-08:00

Question :PDB managed by
a. NIH b. RCSB c.EBI d. PIR
Answer :b

ExPASy used for

2009-02-27T22:13:00.000-08:00

Question :ExPASy used for
a. Nucleic acid analysis b. Protein sequence and structure analysis c. chemical analysis d. All
Answer :b

. How the fasta format file starts

2009-02-27T22:12:00.000-08:00

Question :How the fasta format file starts:
a. begin b. > c. start d. entry
Answer :b

How the Genbank format sequence starts

2009-02-27T22:11:00.000-08:00

Question :How the Genbank format sequence starts
a. Origin b. sequence c. start d. None
Answer :a

PDB stands for

2009-02-27T22:10:00.000-08:00

Question :PDB stands for
a.Public DNA Bank b. Protein Data Bank c. Protein DNA Bank d. All of the above
Answer :b

Which is the submission system for EBI

2009-02-27T22:09:00.000-08:00

Question :Which is the submission system for EBI
a. Webin b. Saskura c. Bankit d. None
Answer :a

What is the system used for searching NCBI data

2009-02-27T22:07:00.002-08:00

Question :What is the system used for searching NCBI data
a. Entrez b. SRS c. google d. Bankit
Answer :a

Which is the literature database of the following

2009-02-27T22:07:00.001-08:00

Question :Which is the literature database of the following:
a. GEO b. PubMed c. EST d. MMDB
Answer :b

Tool used in NCBI to identify similar protein 3 D structures

2009-02-27T22:05:00.000-08:00

Question :Tool used in NCBI to identify similar protein 3 D structures:
a. DALI b. LUDI c. VAST d. BLAST
Answer :c

EST means

2009-02-27T22:04:00.000-08:00

Question :EST means
a. Expressed sequence tags b. Extreme sequence tags c. Extended sequence tags d. All
Answer :a

Genbank is updated

2009-02-27T22:03:00.000-08:00

Question :Genbank is updated
a. Per week b. Daily c. Monthly d. yearly
Answer :B

Which is the identifier in Genbank

2009-02-27T22:01:00.000-08:00

Question : Which is the identifier in Genbank?
a. Entry Name b. Locus c. both d. None
Answer :B